How to configure http://mydomain.in:5280/http-bind on Windows server

Hi,
I have installed ejabberd server on windows server 2008 and running fine.
The local http bind path working fine.

As I have configured ejabberd for www.mydomain.inand I am using ManagedFusion Rewrite Handler for proxy like

RewriteRule ^/httpbind http://mydomain.in:5280/http-bind [P]

But when I try to open http://mydomain.in/httpbind it gives the following error

[Fiddler] The socket connection to mydomain.in failed.
ErrorCode: 10060.
A connection attempt failed because the connected party did not properly respond after a period of time, or established connection failed because connected host has failed to respond xxx.xx.xx.xxx:5280

My question:

What is the reason?

Should I open port 5280 (it is behind a Hardware Firewall) on the server?

How do I communicate from strophe.js to http://mydomain.in:5280/http-bind ?

Any direction would be kind enough. (ASAP)

Thanks in advance